Brain of Iso'rath

The Brain of Iso'rath is the final boss of the Iso'rath quest chain in the Twilight Highlands.

It is fought in Nightmare (quest) along side four shaman of the Earthen Ring.

While the brain's massive health pool may seem intimidating at first, your shaman allies place numerous buffs on you that allow the player to win such as Earth Shield, Heroism, and several totem buffs. The brain's damage from Mind Flay is negligible. During the fight, the player must keep the "Digestion Meter" down by staying inside the protective bubble the shaman place, in addition to avoiding the geysers of acid erupting from the floor. If the meter gets past 50%, the sides of your screen will turn green and you will begin taking damage.

This quest sometimes shows notable glitches such as:

• The shaman not appearing.
• The shaman not attacking Iso'rath when you do.
• Iso'rath permanently evading.